6
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T61311 | HIV-1 inhibitor-30 | ||
HIV-1 inhibitor-30 (compound 10i) is a potent inhibitor of HIV-1, specifically targeting the RT DNA polymerase enzyme. It exhibits strong antiretroviral activity, with an EC 50 value of 40 nM and an IC 50 value of 80 nM.... | |||
T16791 | Rottlerin | Mallotoxin,NSC 56346,NSC 94525 | CaMK , Apoptosis , Others , HIV Protease , PKA , PKC , Autophagy |
Rottlerin (NSC-56346) is a natural product purified from Mallotus Philippinensis and is a specific PKC inhibitor (IC50: PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKCε,η,ζ of 80-100 μM). Rottlerin causes apoptosis via caspase... | |||
T30791 | Censavudine | OBP 601,BMS 986001,BMS-986001,OBP601,BMS986001,OBP-601 | HIV Protease , Reverse Transcriptase |
Censavudine (OBP-601) is a nucleoside analog, a nucleoside reverse transcriptase inhibitor, used for the prevention and treatment of human immunodeficiency virus 1 (HIV-1).Censavudine inhibits HIV-2 and HIV-1. Censavudin... | |||
T72563 | HIV-1 inhibitor-49 | ||
HIV-1 Inhibitor-49, a HEPT analog, is an orally active non-nucleoside reverse transcriptase inhibitor with potent activity against HIV-1, demonstrating an IC 50 of 30 nM. It features an excellent pharmacokinetic profile ... | |||
T74516 | CI-39 | ||
CI-39, a natural antiviral product, serves as a non-nucleoside reverse transcriptase inhibitor (NNRTI) targeting wild type HIV-1. It exhibits an effective concentration (EC50) of 3.40 µM against the virus, while its cyto... | |||
T68457 | GSK812397 | ||
GSK812397 is a potent entry inhibitor of X4-tropic strains of HIV-1, as demonstrated in multiple in vitro cellular assays. GSK812397 is a noncompetitive antagonist of the CXCR4 receptor, with GSK812397 producing a concen... |